Category: Degenerative

Surgery for lumbar spinal stenosis. Attempted meta-analysis of the literature.

This paper published by Turner et al in 1992 represented an attempted meta-analysis  of the literature covering a 24 year period (1996-1990).  Based on the methods described by the authors, 74 studies met the inclusion criteria. One of the major issues in trying to include or exclude studies was a lack of a standardized outcome […]

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Abnormal magnetic-resonance scans of the cervical spine in asymptomatic subjects. A prospective investigation.

This classic paper published by Boden et al (1990) is a parallel study to the one investigating abnormal magnetic resonance imaging scans of the lumbar spine in asymptomatic subjects that was published the same year. This study included 63 asymptomatic volunteers who were screened and underwent an MRI scan of the cervical spine. The MRI […]

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Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis.

This study by Hilibrand et al remains one of the most widely cited studies in regarding adjacent segment disease following anterior cervical discectomy and fusion.   The study population of 374 consecutive patients (409 fusions) were followed prospectively for the development of adjacent segment disease, as defined by symptomatic radiculopathy or myelopathy, at an adjacent segment […]

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2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group.

This multicenter, randomized control trial out of Sweden was the 2001 Volvo Award Winner in Clinical Studies.   Fritzell et al randomized 294 patients into a surgical treatment group (n=222) versus a non-surgical group (N=72).  Patients were randomly assigned treatment and multiple validated outcome measures were utilized.  The overall goal of the study was to define “if lumbar fusion […]

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Accelerated degeneration of the segment adjacent to a lumbar fusion.

The study published by Lee in 1988 was intended to descriptively define conditions and pathomechanics at adjacent segments following a lumbar fusion.  This was at a time period where the effectiveness of lumbar fusion for low back pain was one of the foremost questions to be answered and potential complications of the procedure were largely […]

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Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis.

This study published by the late Dr. Harry Herkowitz, from William Beaumont Hospital in 1991, is one of the most influential papers of its time. His contributions to the field of degenerative spinal surgery continue to influence current research and treatment of many spinal disorders. This paper in particular, has been referenced over 800 times […]

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A prospective, randomized study of lumbar fusion. Preliminary results.

This  randomized study published in 1993 was one of the first to compare instrumentation to no instrumentation using the prospective approach.  One hundred and twenty four patients were included in this study who underwent surgery for a degenerative lumbar condition that included isthmic and degenerative spondylolisthesis, degenerative disc disease, scoliosis with spinal stenosis and repair […]

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Outcome measures for low back pain research. A proposal for standardized use.

Dr. Richard Deyo remains one of the most influential physicians and researchers largely in the area of low back pain having published over 300 peer reviewed articles. His work has included focus in outcome measures, evidenced based practice and management of back pain, health policy and economics of care. This paper published in 1998 represents […]

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1987 Volvo award in clinical sciences. A new clinical model for the treatment of low-back pain.

This classic paper published by Dr. Gordon Waddell in 1987 has been cited over 1577 times. The paper is not a study, but rather a comprehensive review of the literature from the 1970’s and 1980’s looking at the trend of increasing rates of disability associated with low back pain. Dr. Waddell used this information to […]

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Magnetic resonance imaging of the lumbar spine in people without back pain.

This study published in 1994 was similar to that of one of the most widely cited studies looking at the presence of abnormal findings on MRI scans in asymptomatic patients by Boden et al (1990).    Jensen et al evaluated the lumbar MRI scans of 98 asymptomatic volunteers and 27 patients that were symptomatic with low […]

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