Tag: Spondylolisthesis

Decompression and Coflex interlaminar stabilization compared with decompression and instrumented spinal fusion for spinal stenosis and low-grade degenerative spondylolisthesis: two-year results from the prospective, randomized, multicenter, Food and Drug Administration Investigational Device Exemption trial.

Posted: August 23, 2016 at 11:26 am   /   Degenerative

By most definitions, this is a good  example of a randomized control trial (RCT).  The study populations were well matched and the outcomes were standardly measured.  The follow-up rate was greater than 80%. The inclusion criteria included the presence of back pain (VAS of 5/10 or more),  along with spinal stenosis and up to grade […]

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The natural history of spondylolysis and spondylolisthesis.

Posted: December 5, 2015 at 8:27 am   /   Developmental

This is a classic Spine Study looking at the natural history of spondylolysis and spondylolisthesis in a population of 500 first grade students in a small community bordering New York and Pennsylvania. The initial enrollment period was 1954 to 1957.  The inclusion criteria was that the first grader had parental permission and attended one of […]

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1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation.

Posted: December 5, 2015 at 8:23 am   /   Degenerative

This prominent historical study by Fischgrund et al published in 1997, was a well-controlled randomized trial looking at both clinical and radiographic outcomes of lumbar laminectomy with arthrodesis surgery in patients with degenerative spondylolisthesis and spinal stenosis. Patients in this study (N=68) were randomly assigned to two treatment groups; Lumbar laminectomy with posterolateral intertransverse process […]

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Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis.

Posted: December 5, 2015 at 7:49 am   /   Degenerative

This study published by the late Dr. Harry Herkowitz, from William Beaumont Hospital in 1991, is one of the most influential papers of its time. His contributions to the field of degenerative spinal surgery continue to influence current research and treatment of many spinal disorders. This paper in particular, has been referenced over 800 times […]

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A prospective, randomized study of lumbar fusion. Preliminary results.

Posted: December 2, 2015 at 3:20 pm   /   Degenerative

This  randomized study published in 1993 was one of the first to compare instrumentation to no instrumentation using the prospective approach.  One hundred and twenty four patients were included in this study who underwent surgery for a degenerative lumbar condition that included isthmic and degenerative spondylolisthesis, degenerative disc disease, scoliosis with spinal stenosis and repair […]

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