Tag: Female

Role of Weekly Teriparatide Administration in Osseous Union Enhancement within Six Months After Posterior or Transforaminal Lumbar Interbody Fusion for Osteoporosis-Associated Lumbar Degenerative Disorders: A Multicenter, Prospective Randomized Study.

Posted: February 24, 2020 at 8:57 pm   /   Degenerative

With the aging or a population, there has been significant increases in the number of patients receiving lumbar fusion operations secondary to spinal stenosis or spondylolisthesis with spinal stenosis.  Unfortunately, bone quality has bearing on the success  of lumbar fusions.  This paper is a 6 month randomized prospective study on the use of weekly subcutaneous […]

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Assessing the utility of a clinical prediction score regarding 30-day morbidity and mortality following metastatic spinal surgery: the New England Spinal Metastasis Score (NESMS).

Posted: January 26, 2020 at 5:33 pm   /   Oncology

Patients with spinal metastasis are associated with many medical comorbidities.  While surgical management for spine metastasis can improve quality of life, and improve function, The potential for complication, and worsening outcomes must be considered. This paper reviewed patient data from participating centers from 2007 to 2013 And assessed the 30 day mortality and morbidity for […]

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Decompression and Coflex interlaminar stabilization compared with decompression and instrumented spinal fusion for spinal stenosis and low-grade degenerative spondylolisthesis: two-year results from the prospective, randomized, multicenter, Food and Drug Administration Investigational Device Exemption trial.

Posted: August 23, 2016 at 11:26 am   /   Degenerative

By most definitions, this is a good  example of a randomized control trial (RCT).  The study populations were well matched and the outcomes were standardly measured.  The follow-up rate was greater than 80%. The inclusion criteria included the presence of back pain (VAS of 5/10 or more),  along with spinal stenosis and up to grade […]

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Minimum 25-year outcome and functional assessment of lumbar discectomy.

Posted: July 12, 2016 at 1:59 pm   /   Degenerative

This paper is a retrospective review on 348 consecutive patients who had lumbar discectomy surgery between 1973 and 1979 by the orthopedic department of Federico II Hospital in Naples, Italy.   Seven different surgeons participated in the surgical treatments.   Two Hundred One (201)  patients agreed to participate in follow-up,  either by mail or by an in […]

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The Neck Disability Index: a study of reliability and validity.

Posted: May 31, 2016 at 8:51 am   /   Degenerative, General Spine

The Neck Disability Index (NDI) was developed by Vernon and Mior in the late 1980’s and published in 1991. It remains the most widely used outcome instrument for the assessment of patients with neck related disorders. The NDI was developed to provide an objective measure to assess activities of daily living (ADL) in patients with […]

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Long-term outcomes of surgical and nonsurgical management of sciatica secondary to a lumbar disc herniation: 10 year results from the maine lumbar spine study.

Posted: May 26, 2016 at 1:19 pm   /   Degenerative

The debate of surgical management vs. nonsurgical care for the treatment of sciatica resulting from a lumbar disc herniation remains ongoing. This study by Atlas et al (2005) represents a long term prospective investigation looking at the outcomes of surgery vs. conservative treatment up to ten years for patients with sciatica due to a disc […]

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Frequency and clinical predictors of adverse reactions to chiropractic care in the UCLA neck pain study.

Posted: May 24, 2016 at 7:22 am   /   Degenerative

This study by Hurwitz et al from 2005 looked at the type and frequency of adverse events associated with chiropractic treatments for neck pain. Study participants were included if they had neck pain without progressive neurologic deficit or presence of disc herniations. Additionally they were excluded if they had evidence of myelopathy, spondyloarthropathy or were […]

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ISSLS Prize winner: The anatomy of failure in lumbar disc herniation: an in vivo, multimodal, prospective study of 181 subjects.

Posted: February 19, 2016 at 12:05 pm   /   Degenerative

Conventional wisdom states that the mode of failure and cause of disc herniation is secondary to a rupture of nucleus material through the annulus fibrosis. In this paper, the senior author prospectively defined the nature of intraoperatively identified disc herniations in 181 consecutive patients qualified for inclusion. Inclusion criteria included requiring a single level lumbar […]

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The natural history of spondylolysis and spondylolisthesis.

Posted: December 5, 2015 at 8:27 am   /   Developmental

This is a classic Spine Study looking at the natural history of spondylolysis and spondylolisthesis in a population of 500 first grade students in a small community bordering New York and Pennsylvania. The initial enrollment period was 1954 to 1957.  The inclusion criteria was that the first grader had parental permission and attended one of […]

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1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation.

Posted: December 5, 2015 at 8:23 am   /   Degenerative

This prominent historical study by Fischgrund et al published in 1997, was a well-controlled randomized trial looking at both clinical and radiographic outcomes of lumbar laminectomy with arthrodesis surgery in patients with degenerative spondylolisthesis and spinal stenosis. Patients in this study (N=68) were randomly assigned to two treatment groups; Lumbar laminectomy with posterolateral intertransverse process […]

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