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Role of Weekly Teriparatide Administration in Osseous Union Enhancement within Six Months After Posterior or Transforaminal Lumbar Interbody Fusion for Osteoporosis-Associated Lumbar Degenerative Disorders: A Multicenter, Prospective Randomized Study.

With the aging or a population, there has been significant increases in the number of patients receiving lumbar fusion operations secondary to spinal stenosis or spondylolisthesis with spinal stenosis.  Unfortunately, bone quality has bearing on the success  of lumbar fusions.  This paper is a 6 month randomized prospective study on the use of weekly subcutaneous […]

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Five-year Reoperation Rates and Causes for Reoperations Following Lumbar Microendoscopic Discectomy and Decompression.

This is a retrospective review on 441 consecutive patients who underwent micro endoscopic lumbar discectomy or decompression from a single surgeon.  At 5 years,  there was  a 89% followup rate. The reoperation rate was 12.4%. 7% of the had additional surgery secondary to recurrent herniations. A .76% had additional surgery secondary to epidural hematoma. Almost […]

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Cell Therapy for Treatment of Intervertebral Disc Degeneration: A Systematic Review.

Cell therapy treatments for disc degeneration remains a very exciting area of research.  Currently, there are multiple clinics offering forms of these treatments for patients with lower back pain. The science data supporting the use of these techniques remains limited. The Author’s of this paper reviewed Pubmed/MEDLINE data through October 31, 2018, as well as […]

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The influence of obesity on the outcome of treatment of lumbar disc herniation: analysis of the Spine Patient Outcomes Research Trial (SPORT).

This publication by Rihn et al represents a retrospective analysis of data collected from the Spine Patient Outcomes Research Trial (SPORT).   As has been previously published describing the SPORT trial, participants were either randomized or placed in an observational cohort. This data presented was taken from the as-treated analysis and therefore the randomization effect was […]

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The Effects of Smoking and Smoking Cessation on Spine Surgery: A Systematic Review of the Literature.

This systematic review by Jackson and Devine provides us with a current review of the literature in regards to the effects of smoking and smoking cessation on spine surgery.  While this review covers spine surgery in general, our reviewed focused solely on the effects related to cervical disc surgery. There are several potential risks that […]

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The Norwegian Cervical Arthroplasty Trial (NORCAT): 2-year clinical outcome after single-level cervical arthroplasty versus fusion-a prospective, single-blinded, randomized, controlled multicenter study.

This investigation by Sundseth et al presents a prospective randomized study comparing cervical anterior discectomy and fusion (using interbody cage) versus cervical disc arthroplasty in a Norwegian population. Outcomes were determined at 2 years, which is a relatively short time period. Outcome measures included the Neck Disability Index (NDI), SF36, and EuroQol-5D-3L. Overall, this multicenter […]

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Decompression and Coflex interlaminar stabilization compared with decompression and instrumented spinal fusion for spinal stenosis and low-grade degenerative spondylolisthesis: two-year results from the prospective, randomized, multicenter, Food and Drug Administration Investigational Device Exemption trial.

By most definitions, this is a good  example of a randomized control trial (RCT).  The study populations were well matched and the outcomes were standardly measured.  The follow-up rate was greater than 80%. The inclusion criteria included the presence of back pain (VAS of 5/10 or more),  along with spinal stenosis and up to grade […]

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Minimum 25-year outcome and functional assessment of lumbar discectomy.

This paper is a retrospective review on 348 consecutive patients who had lumbar discectomy surgery between 1973 and 1979 by the orthopedic department of Federico II Hospital in Naples, Italy.   Seven different surgeons participated in the surgical treatments.   Two Hundred One (201)  patients agreed to participate in follow-up,  either by mail or by an in […]

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The Neck Disability Index: a study of reliability and validity.

The Neck Disability Index (NDI) was developed by Vernon and Mior in the late 1980’s and published in 1991. It remains the most widely used outcome instrument for the assessment of patients with neck related disorders. The NDI was developed to provide an objective measure to assess activities of daily living (ADL) in patients with […]

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Long-term outcomes of surgical and nonsurgical management of sciatica secondary to a lumbar disc herniation: 10 year results from the maine lumbar spine study.

The debate of surgical management vs. nonsurgical care for the treatment of sciatica resulting from a lumbar disc herniation remains ongoing. This study by Atlas et al (2005) represents a long term prospective investigation looking at the outcomes of surgery vs. conservative treatment up to ten years for patients with sciatica due to a disc […]

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